Men and women are different biologically and organically but to treat the same ills have used the same treatment. But a group of scientists came the doubt: if there was need different drugs for sex?
The test was done taking into account the most widely used drug, namely aspirin, which is also used daily by millions of people to prevent the risk of myocardial infarction. And considering 23 trials over forty years, discovered that aspirin therapy for women was almost useless, and then actually taking drugs without receiving benefits, all suffering damage due to side effects.
This study, published by Todd Yerman University of British Columbia is one of a long series of investigations that are creating the possibility of testing new drugs specific to men and women.
The disease manifests itself differently between the sexes and medicine for centuries has used male mice in preclinical testing of drugs. This is what we firmly support the March issue of Science magazine, the official organ of the American Association for the Advancement of Science. And just to elaborate on this aspect, in Padua in October we will be the second national congress on gender medicine, organized by the National Research Center on Health and Medicine Gender and the Fondazione Giovanni Lorenzini.
Among the scientific results that have the certainty that there are gender differences in manifestations of certain diseases, we refer to those affecting the stomach or lungs.
Regarding the stomach there are two different types of ulcer, gastric ulcer, women are subject (the injury is caused by gastric juices), men rather than duodenal (first part that affects the intestines). It is more likely to cure an ulcer in women than in men and this is due to female hormones, progesterone in fact, that inhibits the formation of gastric juice, in conjunction with estrogens play a major line of mucosal defense.
Regarding lung cancer, all data in the possession of the Italian Cancer Registries show us that the worst damage they suffered by women. For some experiments Carolyn Dresler, International Agency for Research on Cancer in Lyon, found that a specific combination of levels of two enzymes leads to an increased risk of developing lung cancer and this situation occurs especially among women. The female also has a tendency to a genetic mutation that predisposes to the disease that blocks DNA repair mechanisms. But this “failure” is that women respond better to certain drugs, for example, those based on platinum is used for containing chemotherapy or erlotinib and gefitinib (molecules that affect the growth factor receptor epiteale, EGFR).